Frisco Hand Center, PLLC

​Call us:  (214) 618-5719

Dr. Allen has performed close to a hundred of the Xiaflex protocols, and is considered by the manufacturer as a preferred, master user.  He is happy to discuss the process with you, as well as the pluses and minuses of Xiaflex compared to all other treatment methods currently available.  Call the office today for an honest, informative, and no obligation consultation.  Ultimately the decision is yours, and Dr. Allen wants to help you make the most informed choice. 

Xiaflex is a newer, FDA approved, injectable medication that can be used for the treatment of Dupuytren's contracture.  It is a collagenase (collagenase clostridium histolyticum) that specifically attacks and breaks down the collagen fibers associated with Dupuytren's contracture.  It thereby weakens the cord formation(s) and allows them to be manipulated and ruptured.  It is an in-office procedure.  Dr. Allen typically performs the injection portion of the protocol on a Monday or Wednesday, and the manipulation portion of the protocol is then carried out roughly 48 hours later on a corresponding Wednesday or Friday.  Local anesthetic is used for the manipulation portion.  A hand splint is fashioned and worn for the following 2-4 weeks while sleeping and part time during the day.  Recovery time is typically 4 weeks or less.  Hand therapy is occasionally needed, but not routinely.  In general, Xiaflex is cheaper, quicker, and less painful than surgery.  Recurrence rates are similar, as any treatment method utilized for Dupuytren's contracture addresses the cord formation and not the underlying genetic disorder.  Dr. Allen now uses Xiaflex almost exclusively for the treatment of Dupuytren's contracture.